The 24-year-old from Karnataka jumped a height of 1.74 metres in the F42 final, finishing behind Fiji’s Iliesa Delana.
Nagarajegowda, who suffers from a leg impairment, jumped a personal best to become the first Indian to win a Paralympic medal in the event.
The silver for Nagarajegowda helped India better their performance in Beijing four years ago when they didn’t win a medal. India’s best Paralympic performance was at the Athens Games with a gold and a bronze.
Ten Indian athletes, including Nagarajegowda, are taking part in the 2012 Games which end on Sept 9.