Both teams are eyeing their fourth final of the tournament, with the winner set to face Quetta Gladiators in the trophy match on Sunday.
The Qalandars have made one change to their playing XI, bringing in Rishad Hossain in place of Zaman Khan.
On the other hand, Islamabad United made three changes as Haider Ali, Tymal Mills, and Muhammad Shahzad come in place of Ghazi Ghori, Alex Hales, and Ben Dwarshuis.
Islamabad United: Shadab Khan (Captain), Sahibzada Farhan, Rassie van der Dussen, Haider Ali, Agha Salman, James Neesham, Imad Wasim, Tymal Mills, Naseem Shah, Muhammad Shahzad, Salman Irshad.
Lahore Qalandars: Shaheen Afridi (Captain), Fakhar Zaman, Mohammad Naeem, Abdullah Shafique, Kusal Perera, Bhanuka Rajapaksa, Asif Ali, Shakib Al Hasan, Haris Rauf, Rishad Hossain, Salman Mirza.